Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s Disease, is thankfully rather rare. According to a Dutch study the risk is reduced by a large percentage amongst drinkers versus non-drinkers. Smokers, conversely, had a much higher risk.
From the Abstract:
These findings indicate that current smoking is associated with an increased risk of ALS, as well as a worse prognosis, and alcohol consumption is associated with a reduced risk of ALS, further corroborating the role of lifestyle factors in the pathogenesis of ALS. The importance of population-based incident patient cohorts in identifying risk factors is highlighted by this study.